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替米沙坦治疗高血压伴阵发性房颤的效果

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  [摘要]目的 研究并分析替米沙坦治療高血压伴阵发性房颤的临床效果。方法 选取2016年1月~2017年2月本院收治的高血压伴阵发性房颤患者80例作为研究对象,采用随机数字表法分成对照组和观察组,每组40例。对照组采用氨氯地平治疗,观察组采用替米沙坦治疗。比较两组患者的血压、心率、左房内径(LAD)、血清超敏C反应蛋白(hs-CRP)水平和房颤复发率。结果 治疗后,两组患者的血压、心率比较,差异均无统计学意义(P>0.05)。观察组患者的LAD、hs-CRP水平均低于对照组(P<0.05)。观察组患者的房颤复发率明显低于对照组(P<0.05)。结论 替米沙坦治疗高血压伴阵发性房颤可有效降低患者的血压,缩小其左房内径,降低hs-CRP水平,降低房颤复发率。
  [关键词]高血压;阵发性房颤;替米沙坦;血压;心率;超敏C反应蛋白
  [中图分类号] R544.1          [文献标识码] A          [文章编号] 1674-4721(2019)9(a)-0042-03
  Effect of Telmisartan in the treatment of hypertension with paroxysmal atrial fibrillation
  CHEN Zhong-xin1   CHEN Yue-lin2   WU Chu-cai2
  1. Xingyi Special Clinic, Affiliated Zhongshan Hospital of Guangdong Medical University (CHEN Xing-hai Hospital), Guangdong Province, Zhongshan   528415, China; 2. Department of Cardiology, Affiliated Zhongshan Hospital of Guangdong Medical University (CHEN Xing-hai Hospital), Guangdong Province, Zhongshan   528415, China
  [Abstract] Objective To study and analyze the clinical effect of Telmisartan in the treatment of patients with hypertension and paroxysmal atrial fibrillation. Methods Eighty patients with hypertension and paroxysmal atrial fibrillation treated in our hospital from January 2016 to February 2017 were selected as study objects and they were divided into the control group and the observation group using the random number table method, there were 40 cases in each group. The control group was treated with Amlodipine, while the observation group was treated with Telmisartan. The blood pressure, heart rate, left atrial diameter, serum high-sensitivity C-reactive protein (hs-CRP) level and recurrence of atrial fibrillation were compared in patients between the two groups. Results After treatment, there were no significant differences in blood pressure and heart rate in patients between the two groups (P>0.05). The LAD and hs-CRP level in the observation group were lower than those in the control group (P<0.05). The recurrence rate of atrial fibrillation in the observation group was significantly lower than that in the control group (P<0.05). Conclusion Telmisartan in the treatment of hypertension with paroxysmal atrial fibrillation can effectively reduce patients′ blood pressure and LAD, reduce the hs-CRP level, and reduce the recurrence rate of atrial fibrillation.
  [Key words] Hypertension; Paroxysmal atrial fibrillation; Telmisartan; Blood pressure; Heart rate; High-sensitivity C-reactive protein   本研究结果显示,治疗后,两组患者的SBP、DBP、HR比较,差异均无统计学意义(P>0.05)。观察组患者的LAD、hs-CRP水平均低于对照组(P<0.05);同时,观察组患者的复发率明显低于对照组(P<0.05)。
  综上所述,替米沙坦治疗高血压伴阵发性房颤可有效降低患者的血压,缩小患者的LAD,降低hs-CRP水平,降低房颤复发率。
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  (收稿日期:2019-03-11  本文编辑:许俊琴)
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