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肾衰竭患者应用连续性血液透析和间歇性血液透析治疗的临床效果

作者:未知

  【摘要】 目的 研究腎衰竭患者应用连续性血液透析和间歇性血液透析治疗的临床效果。
  方法 100例接受血液透析治疗的肾衰竭患者, 随机分为对照组和观察组, 每组50例。对照组患者接受间歇性血液透析治疗, 观察组患者接受连续性血液透析治疗, 观察并对比两组患者治疗后临床指标[血尿素氮(BUN)、血清肌酐(Scr)、心率(HR)]水平、生活质量评分情况(日常活动评分、社会活动评分、生理功能评分、疼痛感知评分)、低血压和心律失常发生次数。结果 治疗后, 两组患者的BUN、Scr、HR均低于治疗前, 且观察组低于对照组, 差异具有统计学意义(P<0.05);观察组患者的日常活动评分、社会活动评分、生理功能评分分别为(80.66±8.02)、(82.69±8.24)、(81.19±8.13)分, 均高于对照组患者的(68.94±6.82)、(67.62±6.69)、(69.18±6.82)分, 疼痛感知评分为(61.75±6.16)分低于对照组的(80.59±8.04)分, 差异具有统计学意义(P<0.05);观察组患者的低血压发生次数、心律失常发生次数均少于对照组, 差异具有统计学意义(P<0.05)。结论 肾衰竭患者接受连续性血液透析治疗, 可以有效改善患者的临床症状, 提升患者的生活质量, 并减少患者低血压和心律失常的发生次数, 值得推广应用。
  【关键词】 肾衰竭;血液透析;连续性;间歇性
  DOI:10.14163/j.cnki.11-5547/r.2019.17.009
  Clinical effect of continuous hemodialysis and intermittent hemodialysis in the treatment of patients with renal failure   CHEN Ying, YUAN Hong-ying. Weifang Fangzi District People’s Hospital, Weifang 261200, China
  【Abstract】 Objective   To study the clinical effect of continuous hemodialysis and intermittent hemodialysis in the treatment of patients with renal failure. Methods   A total of 100 patients with renal failure undergoing hemodialysis were randomly divided into control group and observation group, with 50 cases in each group. The control group was treated with intermittent hemodialysis, and the observation group was treated with continuous hemodialysis. Observation and comparison were made on clinical indexes [blood urea nitrogen (BUN), serum creatinine (Scr), heart rate (HR)] level, quality of life scores (daily activity score, social activity score, physiological function score, pain perception score), frequency of hypotension and arrhythmia after treatment in two groups. Results   After treatment, both groups had lower BUN, Scr and HR than those before treatment, and the observation group was lower than the control group. Their difference was statistically significant (P<0.05). The observation group had higher daily activity score, social activity score and physiological function score respectively as (80.66±8.02), (82.69±8.24) and (81.19±8.13) points than (68.94±6.82), (67.62±6.69) and (69.18±
  6.82) points in the control group, and lower pain perception score as (61.75±6.16) points than (80.59±
  8.04) points in the control group. Their difference was statistically significant (P<0.05). The observation group had less frequency of hypotension and arrhythmia than the control group, and the difference was statistically significant (P<0.05). Conclusion   Continuous hemodialysis can effectively improve the clinical symptoms of patients with renal failure, improve their quality of life, and reduce the frequency of hypotension and arrhythmia. It is worthy of promotion and application.
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